TL;DR

  • Mississippi pays RNs a BLS median of $74,470 — the more useful number is $85,803, what that paycheck buys after rent and services.
  • RN ranking: #49 on the BLS table, #46 once cost of living is in.
  • Cost of living below the national index lifts real wage by $11,333 over the nominal — a take-home arbitrage that nominal-ranking tables miss.
  • Quartile range $64,050 (bottom 25%) to $83,520 (top 25%); the P10-P90 envelope is $58,130 to $104,040.
  • Mississippi is an NLC compact state — RNs holding a multistate license can practice across compact states without re-applying.

Wage breakdown — Mississippi

Percentile Nominal (BLS) Real (BEA RPP-adjusted)
P10 (entry tier)$58,130$66,976
P25 (lower quartile)$64,050$73,797
P50 (median)$74,470$85,803
P75 (upper quartile)$83,520$96,230
P90 (top tier)$104,040$119,873
Mean$79,470$91,564
Employment29,400 RNs in Mississippi

Cost of living — BEA Regional Price Parity

ComponentMississippi index (US = 100)
All-items RPP86.8
Goods94.4
Services83.5
Rents54.9

Mississippi sits below the national baseline (RPP 86.8), so nominal pay translates to a higher real wage than the BLS median suggests — particularly visible in rents at 54.9.

After-tax take-home — Mississippi (2024 BLS · 2024 tax year, single filer)

Layer-by-layer take-home math at the BLS median

LayerAmountNote
Gross BLS P50 (RN)$74,470nominal median
Federal income tax−$7,63010.2% effective; std deduction $15,750 applied
State income tax−$2,4874.0% above $10K (2026, HB 1733)
FICA (SS 6.2% + Medicare 1.45%)−$5,697SS capped at $183,600 wage base
Take-home (after-tax)$58,65678.8% of gross
Real take-home (RPP-adjusted)$67,582÷ (86.8 / 100) BEA cost-of-living

What the Mississippi state-tax burden means for RN take-home

Mid-band state-tax burden at 3.3% effective. Combined with federal and FICA, take-home is $58,656 (78.8% of gross). After the 86.8 RPP, real take-home is $67,582.

Computed from 2026 IRS federal brackets (Rev. Proc. 2025-32), 2026 state DOR brackets, and 2026 FICA rates. Single filer, standard deduction, no other adjustments. See methodology · tax for limitations (married filers, ITM/SALT itemizers, retirement deferrals, HSA, dependent credits, etc.).

National context

Across the United States, BLS reports a national median of $93,600 for RNs with mean pay of $98,430 and total employment of 3,282,010. Mississippi sits at #49 on nominal pay and #46 on real (cost-adjusted) pay among the 51 states and DC. After cost adjustment, Mississippi climbs 3 positions — the cost of living is favorable relative to the wage.

Licensure — Mississippi (NLC)

Mississippi participates in the Nurse Licensure Compact (NLC), with effective participation since 2017. RNs holding a multistate license issued by another Compact state may practice in Mississippi without applying for a separate Mississippi license. Mississippi-issued multistate licenses are reciprocally recognized in 36 other Compact states (37 jurisdictions total in 2026), eliminating the per-state endorsement workflow ($100–$500 + 4–16 week processing) for travel and per-diem RN work.

Mississippi has been a Compact participant for 9 years as of 2026, putting it among the long-tenured members where the Compact pathway is the established norm at most employers and travel agencies.

Source: NCSBN compact implementation tracker — re-synced quarterly. See NLC reciprocity hub for the cross-state matrix and changelog for status changes.

Frequently asked questions

What is the real (cost-adjusted) RN salary in Mississippi?
After BEA RPP adjustment (regional price parity index 86.8 for Mississippi), the real-wage equivalent is $85,803 — what the $74,470 nominal salary actually buys. Quartiles in real terms: $73,797 to $96,230.
What does the top of the RN pay scale look like in Mississippi?
The 90th percentile lands at $104,040. That tier typically reflects senior roles, specialty certifications, high-cost-of-living metros within the state, or union-negotiated rate cards. Below that, the P75 quartile is $83,520.
How many RNs does Mississippi employ?
BLS OES counts 29,400 RNs employed in Mississippi in the most recent release. Employment density relative to population determines whether wage tiers reflect a robust competitive market or a thinner labor pool.
Is Mississippi a 'real-wage arbitrage' state for RNs?
Yes — the BEA RPP of 86.8 is below the national 100 baseline, so nominal $74,470 stretches to a real-wage equivalent of $85,803. The take-home advantage versus a higher-RPP state is meaningful for RNs comparing offers across regions.
What are the limits of these RN salary numbers?
BLS OES is an employer survey of W-2 wages — it excludes contractor pay, bonuses outside the base wage definition, equity compensation, and tip income. Self-employed practitioners and gig workers are not represented. For occupations with significant non-W-2 income, the BLS figure is a floor, not a complete picture.
How does specialty (ICU, OR, NICU, ER, L&D) affect RN pay in Mississippi?
BLS reports a single 'Registered Nurses' SOC code (29-1141), so the figures on this page are not specialty-segmented. In practice, ICU, NICU, and OR roles in Mississippi typically pay 8-15% above the all-RN median; L&D and ER vary by hospital system. Travel-RN contracts can substantially exceed staff rates during demand spikes.
Travel RN vs staff RN in Mississippi — which earns more on a real basis?
Travel RN gross weekly is usually higher, but the real comparison nets out housing stipends (which are tax-advantaged but state-dependent), per-diem premiums, and the lack of staff-side benefits and pension accrual. In Mississippi, the real-wage gap is narrower than the headline contract numbers suggest.

Sources & methodology

  • U.S. Bureau of Labor Statistics — Occupational Employment and Wage Statistics (OES), SOC 29-1141, 2024 reference period.
  • U.S. Bureau of Economic Analysis — Regional Price Parities, 2023 vintage (all-items, goods, services, rents).
  • Real-wage figures = nominal BLS wage ÷ (state RPP / 100).
  • See the methodology page for full computation details and limitations.

Cross-comparison: see how Mississippi RN pay ranks against the other 254 state × occupation pages on the Real Wage Atlas → — four-way ranking by real wage, after-tax take-home, state-tax savings, and cost-of-living arbitrage.